This article is the eighth in a series exploring the importance of research design, statistical analysis, and epidemiology in nutrition and dietetics research, and the second in a series focused on multivariate statistical analytical techniques. The purpose of this review is to examine the statistical technique, analysis of variance (ANOVA), from its simplest to multivariate applications. Many dietetics practitioners are familiar with basic ANOVA, but less informed of the multivariate applications such as multiway ANOVA, repeated-measures ANOVA, analysis of covariance, multiple ANOVA, and multiple analysis of covariance.