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Fat-Free Mass Depletion and Inflammation in Patients with Bronchiectasis
Journal of the Academy of Nutrition and DieteticsVol. 112Issue 12p1999–2006Published online: November 20, 2012- Gabriel Olveira
- Casilda Olveira
- Inmaculada Gaspar
- Nuria Porras
- Gracia Martín-Núñez
- Elehazara Rubio
- and others
Cited in Scopus: 38Fat-free mass depletion has been related to increased inflammatory activity and to increased morbidity and mortality in chronic respiratory diseases. The aims of our study were to determine the nutritional status and serum levels of adipocytokines and inflammatory cytokines in patients with bronchiectasis of any etiology and their relation with respiratory parameters. A cross-sectional study was designed that included patients aged >14 years with diagnostic criteria for bronchiectasis. Anthropometric parameters; a diet questionnaire; hand grip dynamometry; levels of leptin, adiponectin, interleukin-6 (IL-6), tumor necrosis factor-α, and ultrasensitive C-reactive protein; as well as respiratory parameters (ie, clinical, radiologic, and spirometric values) were assessed.