Skip to Main Content

Fatty Acids

1 Results

Research Research and Professional Briefs
Saturated Fat Intake Modulates the Association between an Obesity Genetic Risk Score and Body Mass Index in Two US Populations
Journal of the Academy of Nutrition and Dietetics
Vol. 114Issue 12p1954–1966Published online: May 1, 2014
- Patricia Casas-Agustench
- Donna K. Arnett
- Caren E. Smith
- Chao-Qiang Lai
- Laurence D. Parnell
- Ingrid B. Borecki
- and others
Cited in Scopus: 49
Combining multiple genetic variants related to obesity into a genetic risk score (GRS) might improve identification of individuals at risk of developing obesity. Moreover, characterizing gene–diet interactions is a research challenge to establish dietary recommendations to individuals with higher predisposition to obesity. Our objective was to analyze the association between an obesity GRS and body mass index (BMI) in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) population, focusing on gene–diet interactions with total fat and saturated fatty acid (SFA) intake, and to replicate findings in the Multi-Ethnic Study of Atherosclerosis (MESA) population.