Skip to Main Content

Pregnancy

1 Results

Research Research and Professional Briefs
Absorption of Folic Acid from a Softgel Capsule Compared to a Standard Tablet
Journal of the Academy of Nutrition and Dietetics
Vol. 112Issue 7p1062–1067Published online: May 11, 2012
- Kevin C. Maki
- Louis I. Ndife
- Kathleen M. Kelley
- Andrea L. Lawless
- James R. Brooks
- Shannon B. Wright
- and others
Cited in Scopus: 5
Consumption of 400 μg folic acid per day from fortified foods and/or supplements, plus food folate from a varied diet is recommended for women of childbearing potential to reduce the risk for neural tube defects during fetal development. This randomized crossover study was designed to evaluate the bioavailability of folic acid from a multivitamin softgel capsule vs a folic acid tablet in 16 premenopausal women (18 to 45 years of age). Participants were randomly assigned to receive a single dose of ∼1,000 μg folic acid in two tablets or ∼1,000 μg folic acid in a multivitamin softgel capsule, and then crossed over to receive the other study product ∼1 week later.