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Research Review
Probiotic Supplementation Has a Limited Effect on Circulating Immune and Inflammatory Markers in Healthy Adults: A Systematic Review of Randomized Controlled Trials
Journal of the Academy of Nutrition and Dietetics
Vol. 120Issue 4p548–564Published online: October 21, 2019
- Alex E. Mohr
- Anthony J. Basile
- Meli’sa S. Crawford
- Karen L. Sweazea
- Katie C. Carpenter
Cited in Scopus: 10
A main mechanism of action proposed for oral probiotic supplementation is immunomodulation, which is expected to impart health benefits in the host by influencing circulating immune and inflammatory factors. To date, the effectiveness of probiotic supplementation for immunomodulation in healthy adults without disease has not been evaluated in a systematic review.