Skip to Main Content

Cancer and Diet

1 Results

Research Original Research
Effects of the Ser326Cys Polymorphism in the DNA Repair OGG1 Gene on Cancer, Cardiovascular, and All-Cause Mortality in the PREDIMED Study: Modulation by Diet
Journal of the Academy of Nutrition and Dietetics
Vol. 118Issue 4p589–605Published online: January 2, 2018
- Dolores Corella
- Judith B. Ramírez-Sabio
- Oscar Coltell
- Carolina Ortega-Azorín
- Ramón Estruch
- Miguel A. Martínez-González
- and others
Cited in Scopus: 15
Oxidatively induced DNA damage, an important factor in cancer etiology, is repaired by oxyguanine glycosylase 1 (OGG1). The lower repair capacity genotype (homozygote Cys326Cys) in the OGG1-rs1052133 (Ser326Cys) polymorphism has been associated with cancer risk. However, no information is available in relation to cancer mortality, other causes of death, and modulation by diet.