Dietary Polyphenol Intake in US Adults and 10-Year Trends: 2007-2016

Published:August 15, 2020DOI:https://doi.org/10.1016/j.jand.2020.06.016

      Abstract

      Background

      Polyphenols are a class of phytochemicals that have antioxidant, anti-inflammatory, anticancer, and antiviral properties. Previous research suggests that dietary polyphenol intake is protective against major chronic diseases. To our knowledge, no data on polyphenol intake for the US adult population are available.

      Objective

      This study explored usual dietary polyphenol intake among US adults in 2013-2016 and examined trends in intake during 2007-2016 by demographic characteristics, and identified major dietary sources of polyphenols.

      Design

      The National Health and Nutrition Examination Survey is a series of cross-sectional surveys representative of the civilian noninstitutionalized US population.

      Participants/setting

      This study included 9,773 adults aged 20 years and older.

      Main outcome measures

      Dietary and supplement data were obtained from two 24-hour dietary recalls. Polyphenol intake was estimated using the Phenol Explorer Database and adjusted for total energy intake.

      Statistical analysis performed

      Usual intake was estimated both overall and by demographic characteristics using the National Cancer Institute method. Trends in intake on a given day over 10 years were evaluated using regression analysis. The complex survey design was incorporated in all analyses.

      Results

      In 2013-2016, the usual intake of dietary polyphenols was a mean (standard error) of 884.1 (20.4) mg per 1,000 kcal/d. Polyphenol intake was higher in adults 40 years and older, women, non-Hispanic White adults, and college graduates. During 2007-2016, the mean daily polyphenol intake did not change significantly over time for overall and demographic groups. Main polyphenol classes consumed were phenolic acids (mean [standard error] of 1,005.6 [34.3] mg/d) and flavonoids (mean [standard error] of 379.1 [10.7] mg/d). Foods and beverages contributed 99.8% of polyphenol intake, with coffee (39.6%), beans (9.8%), and tea (7.6%) as major dietary contributors.

      Conclusion

      Findings from this study suggest that polyphenol intake is consistent with the low intake of fruits, vegetables, and whole grains in the US population, and provide more evidence of the need for increased consumption of these food groups.

      Keywords

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      References

        • Tsao R.
        Chemistry and biochemistry of dietary polyphenols.
        Nutrients. 2010; 2: 1231-1246
        • Pandey K.B.
        • Rizvi S.I.
        Plant polyphenols as dietary antioxidants in human health and disease.
        Oxid Med Cell Longev. 2009; 2: 270-278
        • Koch W.
        Dietary polyphenols-important non-nutrients in the prevention of chronic noncommunicable diseases. A systematic review.
        Nutrients. 2019; 11: 1039
        • Petrescu A.M.
        • Paunescu V.
        • Ilia G.
        The antiviral activity and cytotoxicity of 15 natural phenolic compounds with previously demonstrated antifungal activity.
        J Environ Sci Health B. 2019; 54: 498-504
        • Del Bo C.
        • Bernardi S.
        • Marino M.
        • et al.
        Systematic review on polyphenol intake and health outcomes: Is there sufficient evidence to define a health-promoting polyphenol-rich dietary pattern?.
        Nutrients. 2019; 11: 1355
        • Zamora-Ros R.
        • Knaze V.
        • Rothwell J.A.
        • et al.
        Dietary polyphenol intake in Europe: The European Prospective Investigation into Cancer and Nutrition (EPIC) study.
        Eur J Nutr. 2016; 55: 1359-1375
        • Grosso G.
        • Stepaniak U.
        • Topor-Madry R.
        • Szafraniec K.
        • Pajak A.
        Estimated dietary intake and major food sources of polyphenols in the Polish arm of the HAPIEE study.
        Nutrition. 2014; 30: 1398-1403
        • Song W.O.
        • Chun O.K.
        Tea is the major source of flavan-3-ol and flavonol in the U.S. diet.
        J Nutr. 2008; 138: 1543S-1547S
        • Hanna K.L.
        • O'Neill S.
        • Lyons-Wall P.M.
        Intake of isoflavone and lignan phytoestrogens and associated demographic and lifestyle factors in older Australian women.
        Asia Pac J Clin Nutr. 2010; 19: 540-549
      1. Phenol-Explorer Database. Version 3.6. Institut National de la Recherche Agronomique, Paris, France2015 (Accessed June 1, 2020)
        • Bhagwat S.
        • Haytowitz D.B.
        USDA Database for the Flavonoid Content of Selected Foods. Release 3.2. Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture; 2016.
      2. NHANES questionnaires, datasets, and related documentation. National Center for Health Statistics.
        (Updated February 21, 2020. Accessed June 1, 2020)
        • Curtin L.R.
        • Mohadjer L.K.
        • Dohrmann S.M.
        • et al.
        National Health and Nutrition Examination Survey: Sample design, 2007-2010.
        Vital Health Stat 2. 2013 Aug; : 1-23
      3. NHANES response rates and population totals. National Center for Health Statistics.
        (Updated February 21, 2020. Accessed June 1, 2020)
      4. FNDDS Documentation and Databases. US Department of Agriculture, Agricultural Research Services.
        (Updated October 17, 2019. Accessed June 1, 2020)
      5. NHANES Dietary Supplement Database. National Center for Health Statistics, US Department of Health and Human Services, Centers for Disease Control and Prevention.
        (Updated September, 2019. Accessed June 1, 2020)
        • Perez-Jimenez J.
        • Fezeu L.
        • Touvier M.
        • et al.
        Dietary intake of 337 polyphenols in French adults.
        Am J Clin Nutr. 2011; 93: 1220-1228
        • FoodData Central
        Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, US Department of Agriculture.
        (Published 2019. Accessed June 1, 2020)
        • Rothwell J.A.
        • Medina-Remón A.
        • Pérez-Jiménez J.
        • et al.
        Effects of food processing on polyphenol contents: A systematic analysis using Phenol-Explorer data.
        Mol Nutr Food Res. 2015; 59: 160-170
        • Willett W.C.
        • Howe G.R.
        • Kushi L.H.
        Adjustment for total energy intake in epidemiologic studies.
        Am J Clin Nutr. 1997; 65 (discussion 1229S-1231S): 1220S-1228S
        • Poslusna K.
        • Ruprich J.
        • de Vries J.H.
        • Jakubikova M.
        • van't Veer P.
        Misreporting of energy and micronutrient intake estimated by food records and 24 hour recalls, control and adjustment methods in practice.
        Br J Nutr. 2009; 101: S73-S85
        • Freedman L.S.
        • Schatzkin A.
        • Midthune D.
        • Kipnis V.
        Dealing with dietary measurement error in nutritional cohort studies.
        J Natl Cancer Inst. 2011; 103: 1086-1092
        • Herrick K.A.
        • Rossen L.M.
        • Parsons R.
        • Dodd K.W.
        Estimating usual dietary in take from National Health and Nutrition Examination Survey Data Using the National Cancer Institute Method.
        Vital Health Stat 2. 2018 Feb; : 1-63
        • Dodd K.W.
        • Guenther P.M.
        • Freedman L.S.
        • et al.
        Statistical methods for estimating usual intake of nutrients and foods: A review of the theory.
        J Am Diet Assoc. 2006; 106: 1640-1650
        • Dwyer J.
        • Picciano M.F.
        • Raiten D.J.
        Members of the Steering Committee, National Heath and Nutrition Examination Survey. Estimation of usual intakes: What We Eat in America–NHANES.
        J Nutr. 2003; 133: 609S-623S
      6. SAS/STAT [computer program]. Version 14.3. SAS Institute Inc, Cary, NC2013
        • Burkholder-Cooley N.M.
        • Rajaram S.S.
        • Haddad E.H.
        • Oda K.
        • Fraser G.E.
        • Jaceldo-Siegl K.
        Validating polyphenol intake estimates from a food-frequency questionnaire by using repeated 24-h dietary recalls and a unique method-of-triads approach with 2 biomarkers.
        Am J Clin Nutr. 2017; 105: 685-694
        • Godos J.
        • Marventano S.
        • Mistretta A.
        • Galvano F.
        • Grosso G.
        Dietary sources of polyphenols in the Mediterranean healthy Eating, Aging and Lifestyle (MEAL) study cohort.
        Int J Food Sci Nutr. 2017; 68: 750-756
        • Karam J.
        • Bibiloni M.D.M.
        • Tur J.A.
        Polyphenol estimated intake and dietary sources among older adults from Mallorca Island.
        PLoS One. 2018; 13e0191573
        • Nascimento-Souza M.A.
        • de Paiva P.G.
        • Perez-Jimenez J.
        • do Carmo Castro Franceschini S.
        • Ribeiro A.Q.
        Estimated dietary intake and major food sources of polyphenols in elderly of Vicosa, Brazil: A population-based study.
        Eur J Nutr. 2018; 57: 617-627
        • Taguchi C.
        • Fukushima Y.
        • Kishimoto Y.
        • et al.
        Estimated dietary polyphenol intake and major food and beverage sources among elderly Japanese.
        Nutrients. 2015; 7: 10269-10281
        • Zamora-Ros R.
        • Biessy C.
        • Rothwell J.A.
        • et al.
        Dietary polyphenol intake and their major food sources in the Mexican Teachers' Cohort.
        Br J Nutr. 2018; 120: 353-360
        • Witkowska A.M.
        • Zujko M.E.
        • Waskiewicz A.
        • Terlikowska K.M.
        • Piotrowski W.
        Comparison of various databases for estimation of dietary polyphenol intake in the population of Polish adults.
        Nutrients. 2015; 7: 9299-9308
        • Ivey K.L.
        • Croft K.
        • Prince R.L.
        • Hodgson J.M.
        Comparison of flavonoid intake assessment methods.
        Food Funct. 2016; 7: 3748-3759
        • Miranda A.M.
        • Steluti J.
        • Fisberg R.M.
        • Marchioni D.M.
        Dietary intake and food contributors of polyphenols in adults and elderly adults of Sao Paulo: A population-based study.
        Br J Nutr. 2016; 115: 1061-1070
        • Manach C.
        • Scalbert A.
        • Morand C.
        • Remesy C.
        • Jimenez L.
        Polyphenols: Food sources and bioavailability.
        Am J Clin Nutr. 2004; 79: 727-747
        • Loftfield E.
        • Freedman N.D.
        • Dodd K.W.
        • et al.
        Coffee drinking is widespread in the United States, but usual intake varies by key demographic and lifestyle factors.
        J Nutr. 2016; 146: 1762-1768
        • An R.
        Beverage consumption in relation to discretionary food intake and diet quality among US Adults, 2003 to 2012.
        J Acad Nutr Diet. 2016; 116: 28-37
      7. 2015-2020 Dietary Guidelines for Americans. 8th Edition. US Department of Health and Human Services and US Department of Agriculture.
        (Published December, 2015. Accessed June 1, 2020)
        • Ziauddeen N.
        • Rosi A.
        • Del Rio D.
        • et al.
        Dietary intake of (poly)phenols in children and adults: Cross-sectional analysis of UK National Diet and Nutrition Survey Rolling Programme (2008-2014).
        Eur J Nutr. 2019; 58: 3183-3198
        • Bezerra I.N.
        • Goldman J.
        • Rhodes D.G.
        • et al.
        Difference in adult food group intake by sex and age groups comparing Brazil and United States nationwide surveys.
        Nutr J. 2014; 13: 74
        • Rehm C.D.
        • Penalvo J.L.
        • Afshin A.
        • Mozaffarian D.
        Dietary intake among US adults, 1999-2012.
        JAMA. 2016; 315: 2542-2553
        • Vieux F.
        • Maillot M.
        • Rehm C.D.
        • Drewnowski A.
        Tea consumption patterns in relation to diet quality among children and adults in the United States: Analyses of NHANES 2011-2016 data.
        Nutrients. 2019; 11: 2635
        • Palma-Duran S.A.
        • Vlassopoulos A.
        • Lean M.
        • Govan L.
        • Combet E.
        Nutritional intervention and impact of polyphenol on glycohemoglobin (HbA1c) in non-diabetic and type 2 diabetic subjects: Systematic review and meta-analysis.
        Crit Rev Food Sci Nutr. 2017; 57: 975-986
        • Poti F.
        • Santi D.
        • Spaggiari G.
        • Zimetti F.
        • Zanotti I.
        Polyphenol health effects on cardiovascular and neurodegenerative disorders: A review and meta-analysis.
        Int J Mol Sci. 2019; 20: 351
      8. Polyphenols market size, share & trends analysis report by product (grape seed, green tea, cocoa), by application (beverages, food, feed, dietary supplements, cosmetics), and segment forecasts, 2019-2025. Grand View Research.
        (Published March, 2019. Accessed June 1, 2020)
        • Stice E.
        • Palmrose C.A.
        • Burger K.S.
        Elevated BMI and male sex are associated with greater underreporting of caloric intake as assessed by doubly labeled water.
        J Nutr. 2015; 145: 2412-2418
        • Moshfegh A.J.
        • Rhodes D.G.
        • Baer D.J.
        • et al.
        The US Department of Agriculture Automated Multiple-Pass Method reduces bias in the collection of energy intakes.
        Am J Clin Nutr. 2008; 88: 324-332
        • Subar A.F.
        • Freedman L.S.
        • Tooze J.A.
        • et al.
        Addressing current criticism regarding the value of self-report dietary data.
        J Nutr. 2015; 145: 2639-2645

      Biography

      Q. Huang is a PhD candidate and research associate, Department of Epidemiology and Department of Exercise and Nutrition Sciences; Milken Institute School of Public Health, The George Washington University, Washington, DC.

      Biography

      B. H. Braffett is an associate research professor, Department of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC.

      Biography

      H. A. Young is a professor and vice chair, Department of Epidemiology, Milken Institute School of Public Health, The George Washington University, Washington, DC.

      Biography

      C. L. Ogden is an adjunct professor, Department of Epidemiology; and Milken Institute School of Public Health, The George Washington University, Washington, DC.

      Biography

      S. J. Simmens is a research professor, Department of Biostatistics and Bioinformatics; all at the Milken Institute School of Public Health, The George Washington University, Washington, DC.