Abstract
Background
Obesity and metabolic abnormalities are important risk factors for knee osteoarthritis
(KOA). Recent epidemiologic studies have found that a high glycemic index (GI) and
glycemic load (GL) diet are associated with a higher risk for metabolic complications
and cardiovascular mortality.
Objective
We aimed to examine the association between dietary GI, dietary GL, and KOA among
Korean adults.
Design
This was a cross-sectional study that analyzed data obtained from the Korean National
Health and Nutrition Examination Survey 2010-2012.
Participants/setting
A total of 9,203 participants (5,275 women) aged ≥50 years were included.
Main outcome measures
KOA was defined as the presence of radiographic features of Kellgren-Lawrence grade
≥2. Chronic knee pain was defined as the presence of knee pain for more than 30 days
during the past 3 months. Dietary information was collected using a single 24-hour
recall method.
Statistical analyses performed
The association between the quintiles of dietary GI and dietary GL and knee conditions
was analyzed using a multinomial logistic regression analysis adjusting for age, physical
activity, obesity, hypertension and diabetes, serum low-density lipoprotein, and total
energy intake.
Results
Among the women, the association between dietary GI and symptomatic KOA was: quintile
1: 1.00 (reference); quintile 2: 1.29 (95% CI 0.87 to 1.92); quintile 3: 1.59 (95%
CI 1.11 to 2.28); quintile 4: 1.74 (95% CI 1.21 to 2.51); and quintile 5: 1.77 (95%
CI 1.20 to 2.60) (P=0.001). Chronic knee pain without KOA was associated with dietary GI; however, this
association was not linear across quintiles. There was no significant association
between dietary GI and asymptomatic KOA. Among the men, no significant association
was found between dietary GI and any knee conditions. There was no significant association
between dietary GL and KOA in both men and women.
Conclusions
There was a significant positive association between dietary GI and symptomatic KOA
in women.
Keywords
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Biography
M. W. So is an assistant professor, Department of Internal Medicine, Pusan National University Yangsan Hospital, Gyeongnam.
Biography
S. Lee is an assistant professor, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea.
Biography
S.-H. Kim is a professor, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea.
Article info
Publication history
Published online: February 07, 2018
Accepted:
December 4,
2017
Received:
January 27,
2017
Footnotes
Supplementary materials: Tables 5 and 6 are available at www.jandonline.org
STATEMENT OF POTENTIAL CONFLICT OF INTEREST No potential conflict of interest was reported by the authors.
FUNDING/SUPPORT There is no funding to disclose.
Identification
Copyright
© 2018 by the Academy of Nutrition and Dietetics.
