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Deriving Nutrition Information Using Mathematical Estimation: The Example of Phenylalanine in Sweets with Gelatin

      Diet plays an important role in the management of diseases. A striking example is phenylketonuria (PKU), an inherited metabolic disease that leads to severe mental retardation if left untreated.
      • Kang E.S.
      • Sollee N.D.
      • Gerald P.S.
      Results of treatment and termination of the diet in phenylketonuria (PKU).
      However, a life-long low-phenylalanine diet started shortly after birth enables patients to develop normally and lead productive lives.

      National Institute of Health, October 16-18, 2000. Consensus development conference statement. Phenylketonuria: Screening and management. http://www.nichd.nih.gov/publications/pubs/pku/sub3.cfm. Accessed May 19, 2015.

      A key factor in successful diet management is having readily accessible nutrition information. In that spirit, electronic versions of nutrient databases, such as the US Department of Agriculture’s National Nutrient Database for Standard Reference,

      US Department of Agriculture, Agricultural Research Service, 2014. USDA National Nutrient Database for Standard Reference, release 27. Nutrient Data Laboratory website. http://www.ars.usda.gov/ba/bhnrc/ndl. Accessed May 19, 2015.

      have been made available. But what to do when encountering a food that is not listed in any database?
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      References

        • Kang E.S.
        • Sollee N.D.
        • Gerald P.S.
        Results of treatment and termination of the diet in phenylketonuria (PKU).
        Pediatrics. 1970; 46: 881-890
      1. National Institute of Health, October 16-18, 2000. Consensus development conference statement. Phenylketonuria: Screening and management. http://www.nichd.nih.gov/publications/pubs/pku/sub3.cfm. Accessed May 19, 2015.

      2. US Department of Agriculture, Agricultural Research Service, 2014. USDA National Nutrient Database for Standard Reference, release 27. Nutrient Data Laboratory website. http://www.ars.usda.gov/ba/bhnrc/ndl. Accessed May 19, 2015.

        • Kim J.
        • Boutin M.
        An approximate inverse recipe method with application to automatic food analysis.
        in: Computational Intelligence in Healthcare and e-health (CICARE), 2014 IEEE Symposium. IEEE (Institute of Electrical and Electronics Engineers), Orlando, FL2014: 32-39
      3. Kim J, Boutin M. A list of phenylalanine to protein ratios for common foods. ECE Technical Reports. 2014; Paper 456. http://docs.lib.purdue.edu/ecetr/456. Accessed May 19, 2015.

        • Sweeney A.L.
        • Roberts R.M.
        • Fletcher J.M.
        Dietary protein counting as an alternative way of maintaining metabolic control in phenylketonuria.
        in: JIMD Reports-Case and Research Reports, 2011/3. Springer, Berlin, Germany2012: 131-139