Abstract
Background
Historically, women with metastatic breast cancer are excluded from lifestyle interventions
under the assumptions that diet and physical activity will have little impact on their
disease trajectory. However, recent treatment advances have led to significant increases
in survivorship that pose challenges to this assumption.
Objective
The objectives of this study were to measure dietary intake, physical functioning,
and quality of life in a subset of women with metastatic breast cancer, and to inform
future interventions in this growing population.
Design
Demographics, clinical characteristics, dietary intake, physical functioning, and
quality of life were examined cross-sectionally using validated methodologies.
Participants/setting
Twenty-five women with metastatic breast cancer were recruited during a 4-month period
(June 2014 to September 2014) from two university hospitals in the Midwest that serve
an ethnically diverse patient population. Women completed questionnaires and 24-hour
dietary recalls (1 weekday, 1 weekend).
Main outcome
Lifestyle habits were analyzed.
Statistical analyses
Means (±standard deviations) and frequencies were tallied and t tests were conducted.
Results
On average, participants were 58.8 (±12.8) years of age, predominantly minority, had
been living with metastatic breast cancer for a mean of 36.9 (±29.3) months, and exhibited
significant nutrition-impact symptomology (eg, pain, dry mouth, fatigue). Bone and
lung were the most common sites of metastases. Compared to a larger, normative sample
of women with metastatic breast cancer, study participants displayed similar physical
(P=0.61) and functional well-being scores (P=0.76), but higher social (P=0.10) and emotional well-being scores (P<0.01). The analyses of lifestyle factors showed that the majority of women were overweight
or obese (n=14), not routine exercisers (n=15), and had dietary patterns high in fat
and low in fiber.
Conclusions
This study supports that many women with metastatic breast cancer are in need of carefully
tailored, evidence-based lifestyle strategies that address symptom burden, including
weight management. The implications of diet and physical activity on quality of life
in this population remain unexplored.
Keywords
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Biography
P. Sheean is a post-doctoral research associate, Loyola University Chicago, Marcella Neihoff School of Nursing, Maywood, IL; at the time of the study, she was a post-doctoral research associate at the University of Illinois at Chicago, Chicago, IL.
Biography
C. Kabir is a research specialist, Institute for Research Policy, University of Illinois at Chicago, Chicago, IL.
Biography
M. Stolley is an associate professor, Department of Medicine, Section for Health Promotion Research, University of Illinois at Chicago, Chicago, IL.
Biography
R. Rao is an associate professor of medicine, Department of Medicine, Hematology/Oncology, Rush University Medical Center, Chicago, IL.
Biography
K. Hoskins is an associate professor of medicine, Department of Medicine, Hematology/Oncology, Rush University Medical Center, Chicago, IL.
Article info
Publication history
Published online: May 12, 2015
Accepted:
March 16,
2015
Received:
September 30,
2014
Footnotes
STATEMENT OF POTENTIAL CONFLICT OF INTEREST No potential conflict of interest was reported by the authors.
FUNDING/SUPPORT This work was funded by National Cancer Institute, Cancer Education and Career Development Program (R25CA057699-18).
Identification
Copyright
© 2015 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.
