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Exploring Diet, Physical Activity, and Quality of Life in Females with Metastatic Breast Cancer: A Pilot Study to Support Future Intervention

      Abstract

      Background

      Historically, women with metastatic breast cancer are excluded from lifestyle interventions under the assumptions that diet and physical activity will have little impact on their disease trajectory. However, recent treatment advances have led to significant increases in survivorship that pose challenges to this assumption.

      Objective

      The objectives of this study were to measure dietary intake, physical functioning, and quality of life in a subset of women with metastatic breast cancer, and to inform future interventions in this growing population.

      Design

      Demographics, clinical characteristics, dietary intake, physical functioning, and quality of life were examined cross-sectionally using validated methodologies.

      Participants/setting

      Twenty-five women with metastatic breast cancer were recruited during a 4-month period (June 2014 to September 2014) from two university hospitals in the Midwest that serve an ethnically diverse patient population. Women completed questionnaires and 24-hour dietary recalls (1 weekday, 1 weekend).

      Main outcome

      Lifestyle habits were analyzed.

      Statistical analyses

      Means (±standard deviations) and frequencies were tallied and t tests were conducted.

      Results

      On average, participants were 58.8 (±12.8) years of age, predominantly minority, had been living with metastatic breast cancer for a mean of 36.9 (±29.3) months, and exhibited significant nutrition-impact symptomology (eg, pain, dry mouth, fatigue). Bone and lung were the most common sites of metastases. Compared to a larger, normative sample of women with metastatic breast cancer, study participants displayed similar physical (P=0.61) and functional well-being scores (P=0.76), but higher social (P=0.10) and emotional well-being scores (P<0.01). The analyses of lifestyle factors showed that the majority of women were overweight or obese (n=14), not routine exercisers (n=15), and had dietary patterns high in fat and low in fiber.

      Conclusions

      This study supports that many women with metastatic breast cancer are in need of carefully tailored, evidence-based lifestyle strategies that address symptom burden, including weight management. The implications of diet and physical activity on quality of life in this population remain unexplored.

      Keywords

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      Biography

      P. Sheean is a post-doctoral research associate, Loyola University Chicago, Marcella Neihoff School of Nursing, Maywood, IL; at the time of the study, she was a post-doctoral research associate at the University of Illinois at Chicago, Chicago, IL.

      Biography

      C. Kabir is a research specialist, Institute for Research Policy, University of Illinois at Chicago, Chicago, IL.

      Biography

      M. Stolley is an associate professor, Department of Medicine, Section for Health Promotion Research, University of Illinois at Chicago, Chicago, IL.

      Biography

      R. Rao is an associate professor of medicine, Department of Medicine, Hematology/Oncology, Rush University Medical Center, Chicago, IL.

      Biography

      K. Hoskins is an associate professor of medicine, Department of Medicine, Hematology/Oncology, Rush University Medical Center, Chicago, IL.