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The Effects of Dietary Counseling on Children with Food Allergy: A Prospective, Multicenter Intervention Study

      Abstract

      Although dietary counseling is generally recommended in children with food allergy (FA), its effect on the nutritional status of these patients has not yet been evaluated. Our nonrandomized multicenter prospective intervention study was undertaken to investigate the effects of dietary counseling on children with FA. Anthropometric data, dietary intakes, and laboratory biomarkers of nutritional status were evaluated in children with FA (aged 6 to 36 months) before and after dietary counseling, by multidisciplinary teams composed of pediatricians, dietitians, and nurses. Ninety-one children with FA (49 boys and 42 girls; mean age 18.9 months, 95% CI 16.5 to 21.3) were evaluated; 66 children without FA (41 boys and 25 girls; mean age 20.3 months, 95% CI 17.7 to 22.8) served as controls providing baseline values only. At enrollment, energy and protein intakes were lower in children with FA (91 kcal/kg/day, interquartile range [IQR]=15.1, minimum=55.2, maximum=130.6; and 2.2 g/kg/day, IQR=0.5, minimum=1.5, maximum=2.7, respectively) than in children without FA (96 kcal/kg/day, IQR=6.1, minimum=83.6, maximum=118.0; and 4.6 g/kg/day, IQR=1.2, minimum=2.0, maximum=6.1, respectively; P<0.001). A weight to length ratio <2 standard deviations was more frequent in children with FA than in children without FA (21% vs 3%; P<0.001). At 6 months following dietary counseling, the total energy intake of children with FA was similar to the baseline values of control children. Dietary counseling also resulted in a significant improvement of their anthropometric and laboratory biomarkers of nutritional status. The results of our study support the crucial role of dietary counseling in the clinical management of children with FA.

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      Biography

      R. Berni Canani is a professor, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      L. Leone is a dietitian, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      R. Nocerino is a clinical research nurse, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      S. Ruotolo is a researcher, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      L. Cosenza is a researcher, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      M. Di Costanzo is a physician, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      A. Passariello is a professor, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      A. Coruzzo is a dietitian, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      R. Troncone is a professor, Department of Translational Medicine Science–Pediatric Section, and European Laboratory for the Investigation of Food Induced Diseases, University of Naples “Federico II,” Via Pansini, Naples, Italy.

      Biography

      E. D'Auria is a professor, Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy.

      Biography

      E. Riva is a professor, Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy.

      Biography

      M. Giovannini is a professor, Department of Pediatrics, San Paolo Hospital, University of Milan, Milan, Italy.

      Biography

      G. Terrin is a professor, Department of Womens Health and Territorial Medicine, University of Rome “La Sapienza,” Rome, Italy.

      Biography

      C. Agostoni is a professor, Department of Maternal and Pediatric Sciences, University of Milan, Fondazione IRCCS C Granda Ospedale Maggiore Policlinico, Milan, Italy.