Position of the Academy of Nutrition and Dietetics: Dietary Fatty Acids for Healthy Adults

Published:December 14, 2013DOI:


      It is the position of the Academy of Nutrition and Dietetics (the Academy) that dietary fat for the healthy adult population should provide 20% to 35% of energy, with an increased consumption of n-3 polyunsaturated fatty acids and limited intake of saturated and trans fats. The Academy recommends a food-based approach through a diet that includes regular consumption of fatty fish, nuts and seeds, lean meats and poultry, low-fat dairy products, vegetables, fruits, whole grains, and legumes. These recommendations are made within the context of rapidly evolving science delineating the influence of dietary fat and specific fatty acids on human health. In addition to fat as a valuable and calorically dense macronutrient with a central role in supplying essential nutrition and supporting healthy body weight, evidence on individual fatty acids and fatty acid groups is emerging as a key factor in nutrition and health. Small variations in the structure of fatty acids within broader categories of fatty acids, such as polyunsaturated and saturated, appear to elicit different physiological functions. The Academy recognizes that scientific knowledge about the effects of dietary fats on human health is young and takes a prudent approach in recommending an increase in fatty acids that benefit health and a reduction in fatty acids shown to increase risk of disease. Registered dietitian nutritionists are uniquely positioned to translate fat and fatty acid research into practical and effective dietary recommendations.
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        • American Dietetic Association, Dietitians of Canada
        Position of the American Dietetic Association and Dietitians of Canada: Dietary fatty acids.
        J Am Diet Assoc. 2007; 107: 1599-1611
      1. National Cancer Institute. Sources of saturated fat, stearic acid, & cholesterol raising fat among the US population, 2005–06. Risk Factor Monitoring and Methods website. Updated 2010. Accessed August 2012.

        • Lichtenstein A.H.
        • Appel L.J.
        • et al.
        • American Heart Association Nutrition Committee
        Diet and lifestyle recommendations revision 2006: A scientific statement from the American Heart Association nutrition committee.
        Circulation. 2006; 114: 82-96
        • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
        Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.
        Circulation. 2002; 106: 3143-3421
      2. US Department of Health and Human Services, US Department of Agriculture. Dietary Guidelines for Americans 2010. Updated 2012. Accessed August 12, 2012.

      3. Fats and fatty acids in human nutrition. Report of an expert consultation.
        FAO Food Nutr Pap. 2010; 91: 1-166
      4. The nomenclature of lipids (recommendations, 1976) IUPAC-IUB Commission on Biochemical Nomenclature.
        Biochem J. 1978; 171: 21-35
        • Ratnayake W.M.
        • Galli C.
        Fat and fatty acid terminology, methods of analysis and fat digestion and metabolism: A background review paper.
        Ann Nutr Metab. 2009; 55: 8-43
        • Food and Nutrition Board Institute of Medicine
        Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Dietary Fats: Total Fat and Fatty Acids.
        National Academies Press, Washington, DC2005: 422-541
      5. US Department of Agriculture, Agricultural Research Service. Nutrient intakes from food: Mean amounts consumed per individual, by gender and age, what we eat in America, NHANES 2009-2010. Updated 2012. Accessed September 4, 2012.

        • Khaw K.T.
        • Friesen M.D.
        • Riboli E.
        • Luben R.
        • Wareham N.
        Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: The EPIC-Norfolk prospective study.
        PLoS Med. 2012; 9: e1001255
        • Chiuve S.E.
        • Rimm E.B.
        • Sandhu R.K.
        • et al.
        Dietary fat quality and risk of sudden cardiac death in women.
        Am J Clin Nutr. 2012; 96: 498-507
      6. US Department of Agriculture. USDA National Nutrient Database For Standard Reference. Updated 2011. Accessed September 2, 2012.

        • Mozaffarian D.
        Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death.
        Am J Clin Nutr. 2008; 87: 1991S-1996S
        • Nicolosi R.J.
        Dietary fat saturation effects on low-density-lipoprotein concentrations and metabolism in various animal models.
        Am J Clin Nutr. 1997; 65: 1617S-1627S
      7. Center for Food Safety and Applied Nutrition, Office of Food Additive Safety. Agency response letter GRAS notice no. GRN 000283. September 4, 2009.

        • Ens J.G.
        • Ma D.W.
        • Cole K.S.
        • Field C.J.
        • Clandinin M.T.
        An assessment of c9,t11 linoleic acid intake in a small group of young Canadians.
        Nutr Res. 2001; 21: 955-960
        • Sinclair A.J.
        • Attar-Bashi N.M.
        • Li D.
        What is the role of alpha-linolenic acid for mammals?.
        Lipids. 2002; 37: 1113-1123
        • Davis B.C.
        • Kris-Etherton P.M.
        Achieving optimal essential fatty acid status in vegetarians: Current knowledge and practical implications.
        Am J Clin Nutr. 2003; 78: 640S-646S
        • Burdge G.
        Alpha-linolenic acid metabolism in men and women: Nutritional and biological implications.
        Curr Opin Clin Nutr Metab Care. 2004; 7: 137-144
        • Simopoulos A.P.
        Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: Their role in the determination of nutritional requirements and chronic disease risk.
        Exp Biol Med (Maywood). 2010; 235: 785-795
        • Welch A.A.
        • Shakya-Shrestha S.
        • Lentjes M.A.
        • Wareham N.J.
        • Khaw K.T.
        Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of alpha-linolenic acid to long-chain n-3 polyunsaturated fatty acids: Results from the EPIC-Norfolk cohort.
        Am J Clin Nutr. 2010; 92: 1040-1051
        • Pawlosky R.J.
        • Hibbeln J.R.
        • Novotny J.A.
        • Salem Jr., N.
        Physiological compartmental analysis of alpha-linolenic acid metabolism in adult humans.
        J Lipid Res. 2001; 42: 1257-1265
        • Lattka E.
        • Illig T.
        • Koletzko B.
        • Heinrich J.
        Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism.
        Curr Opin Lipidol. 2010; 21: 64-69
        • Harris W.S.
        • Lemke S.L.
        • Hansen S.N.
        • et al.
        Stearidonic acid-enriched soybean oil increased the omega-3 index, an emerging cardiovascular risk marker.
        Lipids. 2008; 43: 805-811
        • Lemke S.L.
        • Vicini J.L.
        • Su H.
        • et al.
        Dietary intake of stearidonic acid-enriched soybean oil increases the omega-3 index: Randomized, double-blind clinical study of efficacy and safety.
        Am J Clin Nutr. 2010; 92: 766-775
        • Whelan J.
        • Gouffon J.
        • Zhao Y.
        Effects of dietary stearidonic acid on biomarkers of lipid metabolism.
        J Nutr. 2012; 142: 630S-634S
        • Gibson R.A.
        • Neumann M.A.
        • Lien E.L.
        • Boyd K.A.
        • Tu W.C.
        Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids.
        Prostaglandins Leukot Essent Fatty Acids. 2013; 88: 139-146
        • Calder P.C.
        N-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases.
        Am J Clin Nutr. 2006; 83: 1505S-1519S
        • Lauritzen L.
        • Hansen H.S.
        • Jorgensen M.H.
        • Michaelsen K.F.
        The essentiality of long chain n-3 fatty acids in relation to development and function of the brain and retina.
        Prog Lipid Res. 2001; 40: 1-94
      8. US Department of Health and Human Services, Food and Drug Administration. 21 CFR part 184 [docket no. 86G-0289]. June 5, 1997.

        • Blasbalg T.L.
        • Hibbeln J.R.
        • Ramsden C.E.
        • Majchrzak S.F.
        • Rawlings R.R.
        Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century.
        Am J Clin Nutr. 2011; 93: 950-962
        • Kris-Etherton P.M.
        • Harris W.S.
        • Appel L.J.
        • AHA Nutrition Committee. American Heart Association
        Omega-3 fatty acids and cardiovascular disease: New recommendations from the American Heart Association.
        Arterioscler Thromb Vasc Biol. 2003; 23: 151-152
        • National Heart Foundation of Australia
        Fish, Fish Oils, n-3 Polyunsaturated Fatty Acids and Cardiovascular Health. PRO-067.
        2nd ed. National Heart Foundation of Australia, Canberra2008
      9. Food Standards Agency and Department of Health. Scientific Advisory Committee on Nutrition. Advice on Fish Consumption: Benefits and Risks. The Stationary Office, Norwich, UK2004: 1-222
        • Freeman M.P.
        • Hibbeln J.R.
        • Wisner K.L.
        • et al.
        Omega-3 fatty acids: Evidence basis for treatment and future research in psychiatry.
        J Clin Psychiatry. 2006; 67: 1954-1967
      10. European Food Safety Authority (EFSA) Panel on Dietetic Products, Nutrition, and Allergies (NDA). Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol.
        EFSA J. 2010; 8: 1461
      11. International Society for the Study of Fatty Acids and Lipids. Recommendations for intake of polyunsaturated fatty acids in healthy adults. Published 2004. Accessed October 31, 2013.

      12. Food and Drug Administration. Omega-3 fatty acids & coronary heart disease. Docket No. 2003Q-0401. Published September 8, 2004. Accessed October 31, 2013.

      13. US Food and Drug Administration. Qualified health claims: Letter of enforcement discretion—Nuts and coronary heart disease. Docket No 02P-0505. Published July 14, 2003. Accessed October 31, 2013.

        • Bang H.O.
        • Dyerberg J.
        • Nielsen A.B.
        Plasma lipid and lipoprotein pattern in Greenlandic west-coast Eskimos.
        Lancet. 1971; 1: 1143-1145
        • Dyerberg J.
        • Bang H.O.
        • Hjorne N.
        Fatty acid composition of the plasma lipids in Greenland Eskimos.
        Am J Clin Nutr. 1975; 28: 958-966
        • Mozaffarian D.
        • Appel L.J.
        • Van Horn L.
        Components of a cardioprotective diet: New insights.
        Circulation. 2011; 123: 2870-2891
        • Siscovick D.S.
        • Raghunathan T.E.
        • King I.
        • et al.
        Dietary intake and cell membrane levels of long-chain n-3 polyunsaturated fatty acids and the risk of primary cardiac arrest.
        JAMA. 1995; 274: 1363-1367
        • Albert C.M.
        • Campos H.
        • Stampfer M.J.
        • et al.
        Blood levels of long-chain n-3 fatty acids and the risk of sudden death.
        N Engl J Med. 2002; 346: 1113-1118
        • Mozaffarian D.
        • Gottdiener J.S.
        • Siscovick D.S.
        Intake of tuna or other broiled or baked fish versus fried fish and cardiac structure, function, and hemodynamics.
        Am J Cardiol. 2006; 97: 216-222
        • Chung H.
        • Nettleton J.A.
        • Lemaitre R.N.
        • et al.
        Frequency and type of seafood consumed influence plasma (n-3) fatty acid concentrations.
        J Nutr. 2008; 138: 2422-2427
      14. Food and Drug Administration, Environmental Protection Agency. What you need to know about mercury in fish and shellfish. Updated 20042012. Accessed February 5, 2013.

        • Mozaffarian D.
        • Shi P.
        • Morris J.S.
        • et al.
        Mercury exposure and risk of cardiovascular disease in two US cohorts.
        N Engl J Med. 2011; 364: 1116-1125
        • Harris W.S.
        • Pottala J.V.
        • Sands S.A.
        • Jones P.G.
        Comparison of the effects of fish and fish-oil capsules on the n3 fatty acid content of blood cells and plasma phospholipids.
        Am J Clin Nutr. 2007; 86: 1621-1625
        • Harris W.S.
        • Bulchandani D.
        Why do omega-3 fatty acids lower serum triglycerides?.
        Curr Opin Lipidol. 2006; 17: 387-393
        • Roche H.M.
        • Gibney M.J.
        Effect of long-chain n-3 polyunsaturated fatty acids on fasting and postprandial triacylglycerol metabolism.
        Am J Clin Nutr. 2000; 71: 232S-237S
        • Skulas-Ray A.C.
        • Kris-Etherton P.M.
        • Harris W.S.
        • West S.G.
        Effects of marine-derived omega-3 fatty acids on systemic hemodynamics at rest and during stress: A dose-response study.
        Ann Behav Med. 2012; 44: 301-308
        • Cabo J.
        • Alonso R.
        • Mata P.
        Omega-3 fatty acids and blood pressure.
        Br J Nutr. 2012; 107: S195-S200
        • Mozaffarian D.
        • Geelen A.
        • Brouwer I.A.
        • Geleijnse J.M.
        • Zock P.L.
        • Katan M.B.
        Effect of fish oil on heart rate in humans: A meta-analysis of randomized controlled trials.
        Circulation. 2005; 112: 1945-1952
        • Wilk J.B.
        • Tsai M.Y.
        • Hanson N.Q.
        • Gaziano J.M.
        • Djousse L.
        Plasma and dietary omega-3 fatty acids, fish intake, and heart failure risk in the physicians' health study.
        Am J Clin Nutr. 2012; 96: 882-888
        • Kromhout D.
        • Giltay E.J.
        • Geleijnse J.M.
        • Alpha Omega Trial Group
        N-3 fatty acids and cardiovascular events after myocardial infarction.
        N Engl J Med. 2010; 363: 2015-2026
        • Zhao G.
        • Etherton T.D.
        • Martin K.R.
        • West S.G.
        • Gillies P.J.
        • Kris-Etherton P.M.
        Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women.
        J Nutr. 2004; 134: 2991-2997
        • West S.G.
        • Krick A.L.
        • Klein L.C.
        • et al.
        Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function.
        J Am Coll Nutr. 2010; 29: 595-603
        • Zatonski W.
        • Campos H.
        • Willett W.
        Rapid declines in coronary heart disease mortality in eastern Europe are associated with increased consumption of oils rich in alpha-linolenic acid.
        Eur J Epidemiol. 2008; 23: 3-10
        • Kris-Etherton P.M.
        • Hu F.B.
        • Ros E.
        • Sabate J.
        The role of tree nuts and peanuts in the prevention of coronary heart disease: Multiple potential mechanisms.
        J Nutr. 2008; 138: 1746S-1751S
        • King J.C.
        • Blumberg J.
        • Ingwersen L.
        • Jenab M.
        • Tucker K.L.
        Tree nuts and peanuts as components of a healthy diet.
        J Nutr. 2008; 138: 1736S-1740S
        • Banel D.K.
        • Hu F.B.
        Effects of walnut consumption on blood lipids and other cardiovascular risk factors: A meta-analysis and systematic review.
        Am J Clin Nutr. 2009; 90: 56-63
        • Griel A.E.
        • Kris-Etherton P.M.
        • Hilpert K.F.
        • Zhao G.
        • West S.G.
        • Corwin R.L.
        An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humans.
        Nutr J. 2007; 6: 2
        • Harris W.S.
        • Mozaffarian D.
        • Lefevre M.
        • et al.
        Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids.
        J Nutr. 2009; 139: 804S-819S
        • Dewell A.
        • Marvasti F.F.
        • Harris W.S.
        • Tsao P.
        • Gardner C.D.
        Low- and high-dose plant and marine (n-3) fatty acids do not affect plasma inflammatory markers in adults with metabolic syndrome.
        J Nutr. 2011; 141: 2166-2171
        • Woods S.W.
        The economic burden of bipolar disease.
        J Clin Psychiatry. 2000; 61: 38-41
        • Hibbeln J.R.
        Fish consumption and major depression.
        Lancet. 1998; 351: 1213
        • Lin P.Y.
        • Huang S.Y.
        • Su K.P.
        A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression.
        Biol Psychiatry. 2010; 68: 140-147
        • McNamara R.K.
        • Hahn C.G.
        • Jandacek R.
        • et al.
        Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder.
        Biol Psychiatry. 2007; 62: 17-24
        • Su K.P.
        • Huang S.Y.
        • Chiu C.C.
        • Shen W.W.
        Omega-3 fatty acids in major depressive disorder. A preliminary double-blind, placebo-controlled trial.
        Eur Neuropsychopharmacol. 2003; 13: 267-271
        • Appleton K.M.
        • Rogers P.J.
        • Ness A.R.
        Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood.
        Am J Clin Nutr. 2010; 91: 757-770
        • Martins J.G.
        EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: Evidence from a meta-analysis of randomized controlled trials.
        J Am Coll Nutr. 2009; 28: 525-542
        • Heude B.
        • Ducimetiere P.
        • Berr C.
        • EVA S.
        Cognitive decline and fatty acid composition of erythrocyte membranes—The EVA study.
        Am J Clin Nutr. 2003; 77: 803-808
        • Beydoun M.A.
        • Kaufman J.S.
        • Satia J.A.
        • Rosamond W.
        • Folsom A.R.
        Plasma n-3 fatty acids and the risk of cognitive decline in older adults: The atherosclerosis risk in communities study.
        Am J Clin Nutr. 2007; 85: 1103-1111
        • Conquer J.A.
        • Tierney M.C.
        • Zecevic J.
        • Bettger W.J.
        • Fisher R.H.
        Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment.
        Lipids. 2000; 35: 1305-1312
        • Schaefer E.J.
        • Bongard V.
        • Beiser A.S.
        • et al.
        Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: The Framingham Heart Study.
        Arch Neurol. 2006; 63: 1545-1550
        • Dangour A.D.
        • Allen E.
        • Elbourne D.
        • et al.
        Effect of 2-y n-3 long-chain polyunsaturated fatty acid supplementation on cognitive function in older people: A randomized, double-blind, controlled trial.
        Am J Clin Nutr. 2010; 91: 1725-1732
        • Yurko-Mauro K.
        • McCarthy D.
        • Rom D.
        • et al.
        Beneficial effects of docosahexaenoic acid on cognition in age-related cognitive decline.
        Alzheimers Dement. 2010; 6: 456-464
        • Quinn J.F.
        • Raman R.
        • Thomas R.G.
        • et al.
        Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: A randomized trial.
        JAMA. 2010; 304: 1903-1911
        • Muldoon M.F.
        • Ryan C.M.
        • Sheu L.
        • Yao J.K.
        • Conklin S.M.
        • Manuck S.B.
        Serum phospholipid docosahexaenonic acid is associated with cognitive functioning during middle adulthood.
        J Nutr. 2010; 140: 848-853
        • Fortin P.R.
        • Lew R.A.
        • Liang M.H.
        • et al.
        Validation of a meta-analysis: The effects of fish oil in rheumatoid arthritis.
        J Clin Epidemiol. 1995; 48: 1379-1390
        • Goldberg R.J.
        • Katz J.
        A meta-analysis of the analgesic effects of omega-3 polyunsaturated fatty acid supplementation for inflammatory joint pain.
        Pain. 2007; 129: 210-223
        • Yaqoob P.
        • Calder P.C.
        Fatty acids and immune function: New insights into mechanisms.
        Br J Nutr. 2007; 98: S41-S45
        • Johnson G.H.
        • Fritsche K.
        Effect of dietary linoleic acid on markers of inflammation in healthy persons: A systematic review of randomized controlled trials.
        J Acad Nutr Diet. 2012; 112: 1029-1041
        • Mathias R.A.
        • Sergeant S.
        • Ruczinski I.
        • et al.
        The impact of FADS genetic variants on omega6 polyunsaturated fatty acid metabolism in African Americans.
        BMC Genet. 2011; 12: 50
        • Rett B.S.
        • Whelan J.
        Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming western-type diets: A systematic review.
        Nutr Metab (Lond). 2011; 8: 36
        • Harris W.S.
        • Mozaffarian D.
        • Rimm E.
        • et al.
        Omega-6 fatty acids and risk for cardiovascular disease: A science advisory from the American Heart Association nutrition subcommittee of the council on nutrition, physical activity, and metabolism; council on cardiovascular nursing; and council on epidemiology and prevention.
        Circulation. 2009; 119: 902-907
        • Ramsden C.E.
        • Zamora D.
        • Leelarthaepin B.
        • et al.
        Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: Evaluation of recovered data from the Sydney diet heart study and updated meta-analysis.
        BMJ. 2013; 346: e8707
        • Joseph S.V.
        • Jacques H.
        • Plourde M.
        • Mitchell P.L.
        • McLeod R.S.
        • Jones P.J.
        Conjugated linoleic acid supplementation for 8 weeks does not affect body composition, lipid profile, or safety biomarkers in overweight, hyperlipidemic men.
        J Nutr. 2011; 141: 1286-1291
        • Raff M.
        • Tholstrup T.
        • Toubro S.
        • et al.
        Conjugated linoleic acids reduce body fat in healthy postmenopausal women.
        J Nutr. 2009; 139: 1347-1352
        • Norris L.E.
        • Collene A.L.
        • Asp M.L.
        • et al.
        Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus.
        Am J Clin Nutr. 2009; 90: 468-476
        • Riserus U.
        • Arner P.
        • Brismar K.
        • Vessby B.
        Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome.
        Diabetes Care. 2002; 25: 1516-1521
        • Elmadfa I.
        • Kornsteiner M.
        Dietary fat intake—A global perspective.
        Ann Nutr Metab. 2009; 54: 8-14
        • Mensink R.P.
        • Zock P.L.
        • Kester A.D.
        • Katan M.B.
        Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: A meta-analysis of 60 controlled trials.
        Am J Clin Nutr. 2003; 77: 1146-1155
        • Kris-Etherton P.M.
        AHA Science Advisory. Monounsaturated fatty acids and risk of cardiovascular disease. American Heart Association. Nutrition Committee.
        Circulation. 1999; 100: 1253-1258
        • Schwingshackl L.
        • Strasser B.
        • Hoffmann G.
        Effects of monounsaturated fatty acids on cardiovascular risk factors: A systematic review and meta-analysis.
        Ann Nutr Metab. 2011; 59: 176-186
        • Jakobsen M.U.
        • O'Reilly E.J.
        • Heitmann B.L.
        • et al.
        Major types of dietary fat and risk of coronary heart disease: A pooled analysis of 11 cohort studies.
        Am J Clin Nutr. 2009; 89: 1425-1432
        • Warensjo E.
        • Sundstrom J.
        • Vessby B.
        • Cederholm T.
        • Riserus U.
        Markers of dietary fat quality and fatty acid desaturation as predictors of total and cardiovascular mortality: A population-based prospective study.
        Am J Clin Nutr. 2008; 88: 203-209
        • Bullo M.
        • Garcia-Aloy M.
        • Martinez-Gonzalez M.A.
        • et al.
        Association between a healthy lifestyle and general obesity and abdominal obesity in an elderly population at high cardiovascular risk.
        Prev Med. 2011; 53: 155-161
        • Kastorini C.M.
        • Milionis H.J.
        • Esposito K.
        • Giugliano D.
        • Goudevenos J.A.
        • Panagiotakos D.B.
        The effect of Mediterranean diet on metabolic syndrome and its components: A meta-analysis of 50 studies and 534,906 individuals.
        J Am Coll Cardiol. 2011; 57: 1299-1313
        • Nordmann A.J.
        • Suter-Zimmermann K.
        • Bucher H.C.
        • et al.
        Meta-analysis comparing Mediterranean to low-fat diets for modification of cardiovascular risk factors.
        Am J Med. 2011; 124: 841-851.e2
        • Martinez-Gonzalez M.A.
        • Garcia-Arellano A.
        • Toledo E.
        • et al.
        A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: The PREDIMED trial.
        PLoS One. 2012; 7: e43134
        • Estruch R.
        • Ros E.
        • Salas-Salvado J.
        • et al.
        Primary prevention of cardiovascular disease with a Mediterranean diet.
        N Engl J Med. 2013; 368: 1279-1290
        • Kendall C.W.
        • Josse A.R.
        • Esfahani A.
        • Jenkins D.J.
        Nuts, metabolic syndrome and diabetes.
        Br J Nutr. 2010; 104: 465-473
        • Kushi L.H.
        • Doyle C.
        • McCullough M.
        • et al.
        American cancer society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity.
        CA Cancer J Clin. 2012; 62: 30-67
        • Grande F.
        • Anderson J.T.
        • Keys A.
        Comparison of effects of palmitic and stearic acids in the diet on serum cholesterol in man.
        Am J Clin Nutr. 1970; 23: 1184-1193
        • Eckel R.H.
        • Jakicic J.M.
        • Ard J.D.
        • et al.
        2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
        J Am Coll Cardiol. 2013; ([published online ahead of print November 7, 2013])
        • Micha R.
        • Mozaffarian D.
        Saturated fat and cardiometabolic risk factors, coronary heart disease, stroke, and diabetes: A fresh look at the evidence.
        Lipids. 2010; 45: 893-905
        • Mente A.
        • de Koning L.
        • Shannon H.S.
        • Anand S.S.
        A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease.
        Arch Intern Med. 2009; 169: 659-669
        • Franz M.J.
        • Bantle J.P.
        • Beebe C.A.
        • et al.
        Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications.
        Diabetes Care. 2002; 25: 148-198
        • van Dam R.M.
        • Willett W.C.
        • Rimm E.B.
        • Stampfer M.J.
        • Hu F.B.
        Dietary fat and meat intake in relation to risk of type 2 diabetes in men.
        Diabetes Care. 2002; 25: 417-424
        • St-Onge M.P.
        • Bosarge A.
        Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil.
        Am J Clin Nutr. 2008; 87: 621-626
        • St-Onge M.P.
        • Ross R.
        • Parsons W.D.
        • Jones P.J.
        Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men.
        Obes Res. 2003; 11: 395-402
        • Katan M.B.
        • Zock P.L.
        • Mensink R.P.
        Effects of fats and fatty acids on blood lipids in humans: An overview.
        Am J Clin Nutr. 1994; 60: 1017S-1022S
        • Bernstein A.M.
        • Sun Q.
        • Hu F.B.
        • Stampfer M.J.
        • Manson J.E.
        • Willett W.C.
        Major dietary protein sources and risk of coronary heart disease in women.
        Circulation. 2010; 122: 876-883
        • Mir P.S.
        • McAllister T.A.
        • Scott S.
        • et al.
        Conjugated linoleic acid-enriched beef production.
        Am J Clin Nutr. 2004; 79: 1207S-1211S
        • Craig-Schmidt M.C.
        World-wide consumption of trans fatty acids.
        Atheroscler Suppl. 2006; 7: 1-4
        • Hulshof K.F.
        • van Erp-Baart M.A.
        • Anttolainen M.
        • et al.
        Intake of fatty acids in western Europe with emphasis on trans fatty acids: The TRANSFAIR study.
        Eur J Clin Nutr. 1999; 53: 143-157
        • Doell D.
        • Folmer D.
        • Lee H.
        • Honigfort M.
        • Carberry S.
        Updated estimate of trans fat intake by the US population.
        Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012; 29: 861-874
        • Vesper H.W.
        • Kuiper H.C.
        • Mirel L.B.
        • Johnson C.L.
        • Pirkle J.L.
        Levels of plasma trans-fatty acids in non-Hispanic white adults in the United States in 2000 and 2009.
        JAMA. 2012; 307: 562-563
        • Nestel P.
        • Noakes M.
        • Belling B.
        • et al.
        Plasma lipoprotein lipid and lp[a] changes with substitution of elaidic acid for oleic acid in the diet.
        J Lipid Res. 1992; 33: 1029-1036
        • Motard-Belanger A.
        • Charest A.
        • Grenier G.
        • et al.
        Study of the effect of trans fatty acids from ruminants on blood lipids and other risk factors for cardiovascular disease.
        Am J Clin Nutr. 2008; 87: 593-599
        • Hibbeln J.R.
        • Nieminen L.R.
        • Blasbalg T.L.
        • Riggs J.A.
        • Lands W.E.
        Healthy intakes of n-3 and n-6 fatty acids: Estimations considering worldwide diversity.
        Am J Clin Nutr. 2006; 83: 1483S-1493S
        • Mozaffarian D.
        • Micha R.
        • Wallace S.
        Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: A systematic review and meta-analysis of randomized controlled trials.
        PLoS Med. 2010; 7: e1000252
        • Ordovas J.M.
        Nutrigenetics, plasma lipids, and cardiovascular risk.
        J Am Diet Assoc. 2006; 106: 1074-1081
        • Phillips C.M.
        • Goumidi L.
        • Bertrais S.
        • et al.
        Dietary saturated fat modulates the association between STAT3 polymorphisms and abdominal obesity in adults.
        J Nutr. 2009; 139: 2011-2017

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      • Erratum
        Journal of the Academy of Nutrition and DieteticsVol. 114Issue 4
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          In the “Position of the Academy of Nutrition and Dietetics: Dietary Fatty Acids for Healthy Adults,” which appeared in the January 2014 issue of the Journal of the Academy of Nutrition and Dietetics (pp 136-153), there was an error in Table 1 on page 139. Percentages of individual fatty acids and fatty acid groups in coconut oil is in error. The percentages should read as follows: SFA, 86.8%; 8:0, 7.4%; 10:0, 5.9%; 12:0, 44.9%; 14:0, 16.9%; 16:0, 7.9%; 18:0, 2.9%; MUFA, 5.9%; 18:1, 5.9%; PUFA, 1.5%; 18:2, 1.5%.
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