Abstract
In healthy normal-weight adults, cinnamon reduces blood glucose concentration and
enhances insulin sensitivity. Insulin resistance, resulting in increased fasting and
postprandial blood glucose and insulin levels, is commonly observed in obese individuals.
The objective of the study was to compare declines in postprandial glycemic response
in normal-weight and obese subjects with ingestion of 6 g ground cinnamon. In a crossover
study, subjects consumed 50 g available carbohydrate in instant farina cereal, served
plain or with 6 g ground cinnamon. Blood glucose concentration, the main outcome measure,
was assessed at minutes 0, 15, 30, 45, 60, 90, and 120. Repeated-measures analysis
of variance evaluated the effects of body mass index (BMI) group, dietary condition,
and time on blood glucose. Paired t-test assessed blood glucose at individual time points and glucose area under the
curve (AUC) between dietary conditions. Thirty subjects between the ages of 18 and
30 years, 15 with BMIs between 18.5 and 24.9 and 15 with BMIs of 30.0 or more, completed
the study. There was no significant difference in blood glucose between the two BMI
groups at any time point. However, in a combined analysis of all subjects, the addition
of cinnamon to the cereal significantly reduced 120-minute glucose AUC (P=0.008) and blood glucose at 15 (P=0.001), 30 (P<0.001), 45 (P<0.001), and 60 (P=0.001) minutes. At 120 minutes, blood glucose was significantly higher with cinnamon
consumption (P<0.001). These results suggest cinnamon may be effective in moderating postprandial
glucose response in normal weight and obese adults.
Keywords
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Biography
A. Magistrelli is a graduate student, Department of Family and Consumer Sciences, Ball State University, Muncie, IN.
Biography
J. C. Chezem is an associate professor of nutrition, Department of Family and Consumer Sciences, Ball State University, Muncie, IN.
Article info
Publication history
Published online: October 24, 2012
Accepted:
July 30,
2012
Footnotes
FUNDING/SUPPORT This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
STATEMENT OF POTENTIAL CONFLICT OF INTEREST No potential conflict of interest was reported by the authors.
Identification
Copyright
© 2012 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.
