Abstract
Heart failure is a common condition in the Western world, particularly among elderly
persons and with an ever-aging population, the incidence is expected to increase.
Diet in the setting of heart failure is important—patients with this condition are
advised to consume a low-salt diet and monitor their weight closely. Nutritional status
of patients with heart failure also is important—those with poor nutritional status
tend to have a poor long-term prognosis. A growing body of evidence suggests an association
between heart failure and micronutrient status. Reversible heart failure has been
described as a consequence of severe thiamine and selenium deficiency. However, contemporary
studies suggest that a more subtle relationship may exist between micronutrients and
heart failure. This article reviews the existing literature linking heart failure
and micronutrients, examining studies that investigated micronutrient intake, micronutrient
status, and the effect of micronutrient supplementation in patients with heart failure,
and focusing particularly on vitamin A, vitamin C, vitamin E, thiamine, other B vitamins,
vitamin D, selenium, zinc, and copper.
Keywords
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Biography
N. A. McKeag is a clinical research fellow, Centre for Public Health, Queen's University Belfast, Institute of Clinical Science B, Belfast, United Kingdom.
Biography
M. C. McKinley is a senior lecturer, Centre for Public Health, Queen's University Belfast, Institute of Clinical Science B, Belfast, United Kingdom.
Biography
J. V. Woodside is a reader, Centre for Public Health, Queen's University Belfast, Institute of Clinical Science B, Belfast, United Kingdom.
Biography
P. P. McKeown is a senior lecturer, Centre for Public Health, Queen's University Belfast, Institute of Clinical Science B, Belfast, United Kingdom.
Biography
M. T. Harbinson is a senior lecturer, Centre for Vision and Vascular Sciences, Queen's University Belfast, Institute of Clinical Science A, Belfast, United Kingdom.
Article info
Publication history
Published online: May 23, 2012
Accepted:
January 19,
2012
Footnotes
STATEMENT OF POTENTIAL CONFLICT OF INTEREST No potential conflict of interest was reported by the authors.
FUNDING/SUPPORT This work was supported by a Northern Ireland Health & Social Care R&D Doctoral Fellowship Award and a Northern Ireland Chest Heart & Stroke Association Grant.
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© 2012 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.
