Consumption of Whole-Grain Cereals during Weight Loss: Effects on Dietary Quality, Dietary Fiber, Magnesium, Vitamin B-6, and Obesity



      While various weight-management approaches produce weight loss, they may differ in dietary quality. We monitored changes in nutrient intakes in overweight and obese subjects on three different weight-management programs.


      Randomized clinical trial (pilot study) with two 12-week phases: phase 1, weekly counseling; phase 2, monitoring only.


      One hundred eighty nonsmoking, sedentary overweight and obese adults began this outpatient study; 134 (body mass index [calculated as kg/m2]=30.9±2.4; age=42.3±1.2 years) were used in analyses.


      Twenty-four weeks of exercise only (control group), hypocaloric diet plus exercise, or hypocaloric diet with fiber-rich whole-grain cereals plus exercise.

      Main Outcome Measures

      At weeks 0, 12, and 24, diet quality was assessed by 3-day food records and body weight was measured.

      Statistical Analyses Performed

      Three-way analysis of variance with repeated measures.


      The hypocaloric diet with fiber-rich whole-grain cereals plus exercise decreased energy intake more than exercise only (P=0.032). By week 12, the hypocaloric diet with fiber-rich whole-grain cereals plus exercise and the hypocaloric diet plus exercise decreased total fat more than exercise only, which was sustained in the hypocaloric diet with fiber-rich whole-grain cereals plus exercise at 24 weeks (P<0.001). At weeks 12 and 24, the hypocaloric diet with fiber-rich whole-grain cereals plus exercise reduced saturated fat intake more than exercise only. The hypocaloric diet with fiber-rich whole-grain cereals plus exercise increased total fiber, insoluble fiber (both P<0.001), magnesium (P=0.004), and vitamin B-6 (P=0.002) intakes more than the hypocaloric diet plus exercise and exercise only. Calcium and vitamin E intakes were inadequate in all groups. Weight loss was similar in the hypocaloric diet with fiber-rich whole-grain cereals plus exercise and the hypocaloric diet plus exercise.


      Weight-reduction strategies may be associated with reduced intake of micronutrients, such as calcium and vitamin E. However, a hypocaloric diet with fiber-rich whole-grain cereal is effective for improving or maintaining other aspects of dietary quality during weight loss.
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        • Cummings S.
        • Parham E.S.
        • Strain G.W.
        Position of the American Dietetic Association.
        J Am Diet Assoc. 2002; 102: 1145-1155
        • Mokdad A.H.
        • Bowman B.A.
        • Ford E.S.
        Prevalence of obesity, diabetes and obesity-related risk factors, 2001.
        JAMA. 2003; 289: 76-79
        • Anderson J.W.
        • Konz E.C.
        • Jenkins D.J.
        Health advantages and disadvantages of weight-reducing diets.
        J Am Coll Nutr. 2001; 19: 578-590
        • Freedman M.R.
        • King J.
        • Kennedy E.
        Popular diets.
        Obes Res. 2001; 9: 1S-40S
        • Melanson K.J.
        • Dwyer J.
        Popular diets for treatment of overweight and obesity.
        in: Wadden T.A. Stunkard A.J. Handbook of Obesity Treatment. The Guilford Press, New York, NY2002: 249-282
        • Morgan K.J.
        • Zabik M.E.
        • Stampley G.L.
        The role of breakfast in diet adequacy of the US adult population.
        J Am Coll Nutr. 1986; 5: 551-563
        • Nicklas T.A.
        • O’Neil C.E.
        • Berenson G.S.
        Nutrient contribution of breakfast, secular trends, and the role of ready-to-eat cereals.
        Am J Clin Nutr. 1998; 67: 757S-763S
        • Siega-Riz A.M.
        • Popkin B.M.
        • Carson T.
        Differences in food patterns at breakfast by sociodemographic characteristics among a nationally representative sample of adults in the United States.
        Prev Med. 2000; 30: 415-424
        • Kleemola P.
        • Puska P.
        • Vartiainen E.
        • Roos E.
        • Luoto R.
        • Ehnholm C.
        The effect of breakfast cereal on diet and serum cholesterol.
        Eur J Clin Nutr. 1999; 53: 716-721
        • Truswell A.S.
        Cereal grains and coronary heart disease.
        Eur J Clin Nutr. 2002; 56: 1-14
        • Slavin J.
        Why whole grains are protective.
        Proc Nutr Soc. 2003; 62: 129-134
        • Slavin J.L.
        • Jacobs D.
        • Marquart L.
        • Wiemer K.
        The role of whole grains in disease prevention.
        J Am Diet Assoc. 2001; 101: 780-785
        • Gross L.S.
        • Li L.
        • Ford E.S.
        • Liu S.
        Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States.
        Am J Clin Nutr. 2004; 79: 774-779
        • Cleveland L.E.
        • Moshfegh A.J.
        • Albertson A.M.
        • Goldman J.D.
        Dietary intake of whole grains.
        J Am Coll Nutr. 2000; 19: 331S-338S
        • Marlett J.A.
        • McBurney M.I.
        • Slavin J.L.
        Position of the American Dietetic Association.
        J Am Diet Assoc. 2002; 102: 993-1000
        • World Health Organization
        Global strategy on diet, physical activity and health. 2004 (Fifty-seventh World Health Assembly WHA57.17 Agenda Item 12.6. Geneva, Switzerland)
      1. US Department of Agriculture. MyPyramid. Available at: Accessed March 24, 2005.

        • Ruxton C.H.
        • Kirk T.R.
        Br J Nutr. 1997; 78: 199-213
        • Mattes R.D.
        Ready-to-eat cereal used as a meal replacement promotes weight loss in humans.
        J Am Coll Nutr. 2002; 21: 570-577
        • Cho S.
        • Dietrich M.
        • Brown C.J.
        • Clark C.A.
        • Block G.
        The effect of breakfast type on total daily energy intake and body mass index.
        J Am Coll Nutr. 2003; 22: 296-302
        • Holt S.H.
        • Delargy H.J.
        • Lawton C.L.
        • Blundell J.E.
        The effects of high-carbohydrate vs high-fat breakfasts on feelings of fullness and alertness, and subsequent food intake.
        Int J Food Sci Nutr. 1999; 50: 13-28
        • Wyatt H.R.
        • Grunwald G.K.
        • Mosca C.L.
        • Klem M.L.
        • Wing R.R.
        • Hill J.O.
        Long-term weight loss and breakfast in subjects in the National Weight Control Registry.
        Obes Res. 2002; 10: 78-82
        • Liu S.
        • Willett W.C.
        • Manson J.E.
        • Hu F.B.
        • Rosner B.
        • Colditz G.
        Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women.
        Am J Clin Nutr. 2003; 78: 920-927
        • Blair S.N.
        • Haskell W.L.
        • Ho P.
        • Paffenbarger Jr, R.S.
        • Vranizan K.M.
        • Farquhar J.W.
        • Wood P.D.
        Assessment of habitual physical activity by a seven-day recall in a community survey and controlled experiments.
        Am J Epidemiol. 1985; 122: 794-804
        • American College of Sports Medicine Position Stand
        The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults.
        Med Sci Sports Exerc. 1998; 30: 975-991
        • Melanson K.J.
        • Dell’Olio J.
        • Carpenter M.R.
        • Angelopoulos T.J.
        Changes in multiple health outcomes at 12 and 24 weeks, resulting from 12 weeks of exercise with or without dietary counseling in obese adults.
        Nutrition. 2004; 20: 849-856
        • American Diabetes Association, American Dietetic Association
        Exchange Lists for Meal Planning. 2nd ed. American Diabetes Association, American Dietetic Association, Alexandria, VA2003
        • Schakel S.F.
        • Sievert Y.A.
        • Buzzard I.M.
        Sources of data for developing and maintaining a nutrient database.
        J Am Diet Assoc. 1988; 88: 1268-1271
        • Nieman D.C.
        • Trone G.A.
        • Austin M.D.
        A new handheld device for measuring resting metabolic rate and oxygen consumption.
        J Am Diet Assoc. 2003; 103: 588-592
        • Weir J.B.
        New methods for calculating metabolic rate with special reference to protein metabolism.
        J Physiol. 1949; 109: 1-9
        • Krauss R.M.
        • Eckel R.H.
        • Howard B.
        • Appel L.J.
        • Daniels S.R.
        • Deckelbaum R.J.
        • Erdman Jr, J.W.
        • Kris-Etherton P.
        • Goldberg I.J.
        • Kotchen T.A.
        • Lichtenstein A.H.
        • Mitch W.E.
        • Mullis R.
        • Robinson K.
        • Wylie-Rosett J.
        • St Jeor S.
        • Suttie J.
        • Tribble D.L.
        • Bazzarre T.L.
        AHA Dietary Guidelines: Revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association.
        Circulation. 2000; 102: 2284-2299
        • Ludwig D.S.
        • Pereira M.A.
        • Kroenke C.H.
        • Hilner J.E.
        • Van Horn L.
        • Slattery M.L.
        • Jacobs Jr, D.R.
        Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults.
        JAMA. 1999; 282: 1539-1546
        • Meyer K.A.
        • Kushi L.H.
        • Jacobs Jr, D.R.
        • Slavin J.
        • Sellers T.A.
        • Folsom A.R.
        Carbohydrates, dietary fiber, and incident type 2 diabetes in older women.
        Am J Clin Nutr. 2000; 71: 921-930
        • Davy B.M.
        • Melby C.L.
        The effect of fiber-rich carbohydrates on features of Syndrome X.
        J Am Diet Assoc. 2003; 103: 86-96
        • Raben A.
        • Christensen N.J.
        • Madsen J.
        • Holst J.J.
        • Astrup A.
        Decreased postprandial thermogenesis and fat oxidation but increased fullness after a high-fiber meal compared with a low-fiber meal.
        Am J Clin Nutr. 1994; 59: 1386-1394
        • Turconi G.
        • Bazzano R.
        • Caramella R.
        • Porrini M.
        • Crovetti R.
        • Lanzola E.
        The effects of high intakes of fibre ingested at breakfast on satiety.
        Eur J Clin Nutr. 1995; 49: S281-S285
        • Delargy H.J.
        • O’Sullivan K.R.
        • Fletcher R.J.
        • Blundell J.E.
        Effects of amount and type of dietary fibre (soluble and insoluble) on short-term control of appetite.
        Int J Food Sci Nutr. 1997; 48: 67-77
        • Pasman W.J.
        • Saris W.H.
        • Wauters M.A.
        • Westerterp-Plantenga M.S.
        Effect of one week of fibre supplementation on hunger and satiety ratings and energy intake.
        Appetite. 1997; 29: 77-87
        • Howarth N.C.
        • Saltzman E.
        • Roberts S.B.
        Dietary fiber and weight regulation.
        Nutr Rev. 2001; 59: 129-139
        • Roberts S.B.
        • McCrory M.A.
        • Saltzman E.
        The influence of dietary composition on energy intake and body weight.
        J Am Coll Nutr. 2002; 21: 140S-145S
        • Birketvedt G.S.
        • Aaseth J.
        • Florholmen J.R.
        • Ryttig K.
        Long-term effect of fibre supplement and reduced energy intake on body weight and blood lipids in overweight subjects.
        Acta Medica (Hradec Kralove). 2000; 43: 129-132
        • Koh-Banerjee P.
        • Franz M.
        • Sampson L.
        • Liu S.
        • Jacobs Jr, D.R.
        • Spiegelman D.
        • Willett W.
        • Rimm E.
        Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men.
        Am J Clin Nutr. 2004; 80: 1237-1245
        • Ervin R.B.
        • Wang C.Y.
        • Wright J.D.
        • Kennedy-Stephenson J.
        Dietary intake of selected minerals for the United States population.
        Adv Data. 2004; : 1-5
        • Ford E.S.
        • Mokdad A.H.
        Dietary magnesium intake in a national sample of US adults.
        J Nutr. 2003; 133: 2879-2882
        • Paolisso G.
        • Sgambato S.
        • Gambardella A.
        • Pizza G.
        • Tesauro P.
        • Varricchio M.
        • D’Onofrio F.
        Daily magnesium supplements improve glucose handling in elderly subjects.
        Am J Clin Nutr. 1992; 55: 1161-1167
        • Rosolova H.
        • Mayer Jr, O.
        • Reaven G.
        Effect of variations in plasma magnesium concentration on resistance to insulin-mediated glucose disposal in nondiabetic subjects.
        J Clin Endocrinol Metab. 1997; 82: 3783-3785
        • Guerrero-Romero F.
        • Rodriguez-Moran M.
        Low serum magnesium levels and metabolic syndrome.
        Acta Diabetol. 2002; 39: 209-213
        • Barbagallo M.
        • Dominguez L.J.
        • Galioto A.
        • Ferlisi A.
        • Cani C.
        • Malfa L.
        • Pineo A.
        • Busardo A.
        • Paolisso G.
        Role of magnesium in insulin action, diabetes and cardio-metabolic syndrome X.
        Mol Aspects Med. 2003; 24: 39-52
        • Tam M.
        • Gomez S.
        • Gonzalez-Gross M.
        • Marcos A.
        Possible roles of magnesium on the immune system.
        Eur J Clin Nutr. 2003; 57: 1193-1197
        • Tucker K.L.
        Dietary intake and bone status with aging.
        Curr Pharm Des. 2003; 9: 2687-2704
        • Vaskonen T.
        Dietary minerals and modification of cardiovascular risk factors.
        J Nutr Biochem. 2003; 14: 492-506
        • Al-Delaimy W.K.
        • Rimm E.B.
        • Willett W.C.
        • Stampfer M.J.
        • Hu F.B.
        Magnesium intake and risk of coronary heart disease among men.
        J Am Coll Nutr. 2004; 23: 63-70
        • Macdonald H.M.
        • New S.A.
        • Golden M.H.
        • Campbell M.K.
        • Reid D.M.
        Nutritional associations with bone loss during the menopausal transition.
        Am J Clin Nutr. 2004; 79: 155-165
        • Ervin R.B.
        • Wright J.D.
        • Wang C.Y.
        • Kennedy-Stephenson J.
        Dietary intake of selected vitamins for the United States population.
        Adv Data. 2004; : 1-4
        • Kim M.K.
        • Ordovas J.M.
        • Selhub J.
        • Campos H.
        B vitamins and plasma homocysteine concentrations in an urban and rural area of Costa Rica.
        J Am Coll Nutr. 2003; 22: 224-231
        • Tucker K.L.
        • Olson B.
        • Bakun P.
        • Dallal G.E.
        • Selhub J.
        • Rosenberg I.H.
        Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations.
        Am J Clin Nutr. 2004; 79: 805-811
        • Friso S.
        • Girelli D.
        • Martinelli N.
        • Olivieri O.
        • Lotto V.
        • Bozzini C.
        • Pizzolo F.
        • Faccini G.
        • Beltrame F.
        • Corrocher R.
        Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk.
        Am J Clin Nutr. 2004; 79: 992-998
        • Harnack L.
        • Jacobs Jr, D.R.
        • Nicodemus K.
        • Lazovich D.
        • Anderson K.
        • Folsom A.R.
        Relationship of folate, vitamin B-6, vitamin B-12, and methionine intake to incidence of colorectal cancers.
        Nutr Cancer. 2002; 43: 152-158
        • Zhang S.M.
        • Willett W.C.
        • Selhub J.
        • Hunter D.J.
        • Giovannucci E.L.
        • Holmes M.D.
        • Colditz G.A.
        • Hankinson S.E.
        Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer.
        J Natl Cancer Inst. 2003; 95: 373-380
        • Merchant A.T.
        • Hu F.B.
        • Spiegelman D.
        • Willett W.C.
        • Rimm E.B.
        • Ascherio A.
        The use of B vitamin supplements and peripheral arterial disease risk in men are inversely related.
        J Nutr. 2003; 133: 2863-2867
        • Mizrahi E.H.
        • Jacobsen D.W.
        • Debanne S.M.
        • Traore F.
        • Lerner A.J.
        • Friedland R.P.
        • Petot G.J.
        Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging.
        J Nutr Health Aging. 2003; 7: 160-165
        • Bruce B.
        • Spiller G.A.
        • Klevay L.M.
        • Gallagher S.K.
        A diet high in whole and unrefined foods favorably alters lipids, antioxidant defenses, and colon function.
        J Am Coll Nutr. 2000; 19: 61-67


      K. J. Melanson is assistant professor at the Department of Nutrition and Food Sciences, University of Rhode Island, Kingston.


      T. J. Angelopoulos is director of Clinical Research, V. T. Nguyen is senior director of Nutrition and Metabolism, L. Zukley is associate director of Clinical Research, J. Lowndes is research associate, T. J. Dube is research associate, J. J. Fiutem is research associate, B. W. Yount is research associate, and J. M. Rippe is director and founder, Rippe Lifestyle Institute at Florida Hospital Celebration Health, Celebration, FL.


      T. J. Angelopoulos is professor and J. Lowndes is research associate, Department of Health Professions, University of Central Florida, Orlando.


      M. Martini is senior scientist, Kraft Foods, Inc, Glenview, IL.