Calcium Intake and 10-Year Weight Change in Middle-Aged Adults



      The goal of this study was to examine the purported effects of calcium on modulating body weight.


      Retrospective data was used to assess the relationship between calcium intake and weight change over an 8- to 12-year period among middle-aged adults.


      Participants were 10,591 men and women aged 53 to 57 years recruited during 2000-2002.

      Statistical Analysis

      Linear regression was used to model associations of 10-year weight change and calcium intake, adjusted for weight at age 45 years, energy intake, physical activity, and other factors.


      Calcium intake was associated with 10-year weight change only in women. Women with current calcium supplement dose of >500 mg/day had a 10-year weight gain of 5.1 kg (95% confidence interval 4.7 to 5.5) compared to 6.9 kg (95% confidence interval 6.5 to 7.4) among nonusers (P for trend=0.001). Trends were similar for total calcium intake from diet plus supplements (P for trend=0.001). Dietary calcium alone had no significant effect on 10-year weight change.


      Increasing total calcium intake, in the form of calcium supplementation, may be beneficial to weight maintenance, especially in women during midlife.
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      A. J. Gonzalez is a graduate research assistant, Fred Hutchinson Cancer Research Center, Public Health Sciences, Seattle, WA, and the Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle


      E. White and A. Kristal are professors, Fred Hutchinson Cancer Research Center, Public Health Sciences, Seattle, WA, and the Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle


      A. J. Littman is a postdoctoral fellow, Fred Hutchinson Cancer Research Center, Public Health Sciences, Seattle, WA, and the Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle